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OND-1: The Truth About the 1990 Cyclosporine Hair Trial
01
15 September 2026
OND-1: The Truth About the 1990 Cyclosporine Hair Trial
Cyclosporine's history as a hair loss candidate goes back further than most pipeline compounds we cover, all the way to a small human trial in 1990, and it t...
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DLQ01: The Experimental Hair Drug That Outperformed Minoxidil
02
14 September 2026
DLQ01: The Experimental Hair Drug That Outperformed Minoxidil
In July 2024, a small Delaware biotech called Dermaliq Therapeutics announced that its topical hair loss candidate, DLQ01, had produced a larger reported inc...
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Sublingual Minoxidil: A New Route Around Oral Minoxidil's Biggest Flaw
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14 September 2026
Sublingual Minoxidil: A New Route Around Oral Minoxidil's Biggest Flaw
Low-dose oral minoxidil has become one of the most widely used off-label hair loss treatments of the past decade, prized for the convenience of a tablet over...
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AMP-303: How Hairy Moles Inspired a New Hair Loss Treatment
04
13 September 2026
AMP-303: How Hairy Moles Inspired a New Hair Loss Treatment
AMP-303 is an injectable treatment from Amplifica Holdings Group, and its origin story is unusual: it traces back to a decade of research into why hairy mole...
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GT20029: The Hair Loss Drug That Destroys Androgen Receptors
05
13 September 2026
GT20029: The Hair Loss Drug That Destroys Androgen Receptors
GT20029 is a topical drug from Kintor Pharmaceutical, the same China-based company behind KX-826 (pyrilutamide), but it works through a meaningfully differen...
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ET-02: The New Hair Loss Treatment Targeting Hair Follicle Stem Cells
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13 September 2026
ET-02: The New Hair Loss Treatment Targeting Hair Follicle Stem Cells
ET-02 is a topical small molecule from Eirion Therapeutics, and it's getting attention for two reasons: an explicitly non-hormonal mechanism aimed at hair fo...
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WNT5A-ATF3-FOSB: The Hair Follicle Pathway Older Research Contradicts
07
11 September 2026
WNT5A-ATF3-FOSB: The Hair Follicle Pathway Older Research Contradicts
A single-cell RNA sequencing study published in the past month has identified a new signalling pathway that appears to be switched off in balding hair follic...
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ABS-201 for Hair Loss: Can Blocking Prolactin Regrow Hair?
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01 September 2026
ABS-201 for Hair Loss: Can Blocking Prolactin Regrow Hair?
Most hair loss drugs in development still work somewhere along the androgen pathway, the same territory finasteride and dutasteride occupy. ABS-201, develope...
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Topical Cetirizine: The Antihistamine That Blocks Balding
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30 August 2026
Topical Cetirizine: The Antihistamine That Blocks Balding
Cetirizine is a second-generation antihistamine, sold over the counter for hay fever and hives. It has no obvious connection to hair. The rationale for using...
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Tretinoin for Hair Loss: Does It Work Without Minoxidil?
10
28 August 2026
Tretinoin for Hair Loss: Does It Work Without Minoxidil?
Tretinoin comes up constantly in hair loss discussions, almost always attached to minoxidil. The standard claim is that tretinoin helps minoxidil work better...
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